Resumen
Prostate cancer affects one out of every eight men over the course of their lifetimes, and recurrence of the disease after initial cancer treatment occurs in almost one-third of men. The aim of our review was to assess the role of salvage radical prostatectomy in patients with prostate cancer recurrence after initial treatment with radiotherapy. Outcome data demonstrate that radical prostatectomy has oncologic benefits, although it incurs several intraoperative and postoperative functional risks including rectal injury, erectile dysfunction, and incontinence. Given that there is no clinical consensus on which management approach is superior for patients with localized prostate cancer recurrence, this review provides evidence that radical prostatectomy offers meaningful cancer control and should be considered for select patients with radiation-resistant disease.