Resumen
Cancer imposes the largest clinical and economic burden, with an estimated 19.3 million cancer incidents and almost 10.0 million cancer deaths in 2020 worldwide. Despite advances in early diagnosis before cancer progression, there are still feared concerns about recurrence after primary treatments. Psychological stress has been known to contribute to the development and progression of cancer; however, its effect on cancer recurrence remains inconclusive. To determine the association between psychological stress and the risk of cancer recurrence, this review aims to systematically evaluate the relevant studies. This study provides comprehensive information about the importance of psychological stress on cancer recurrence and provides reference data to clinicians and scientists for further studies.