Inicio  /  Cancers  /  Vol: 16 Par: 4 (2024)  /  Artículo
ARTÍCULO
TITULO

Individual Survival Distributions Generated by Multi-Task Logistic Regression Yield a New Perspective on Molecular and Clinical Prognostic Factors in Gastric Adenocarcinoma

Daniel Skubleny    
Jennifer Spratlin    
Sunita Ghosh    
Russell Greiner    
Daniel E. Schiller and Gina R. Rayat    

Resumen

Traditional survival models estimate risk across many patients, and thus, translating survival outcomes to individual patients is a difficult task. Individual survival distributions (ISDs) provide an accurate survival curve for each individual patient. In this study, we demonstrate that ISDs established with multi-task logistic regression (MTLR) models provide accurate individual survival predictions for gastric cancer. Because MTLR is not bound by traditional assumptions, we demonstrate that the degree to which a tumour has a favourable immune system interaction has the most relevant long-term survival effects.

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