Inicio  /  Cancers  /  Vol: 14 Par: 13 (2022)  /  Artículo
ARTÍCULO
TITULO

Liquid Biopsy in Prostate Cancer Management?Current Challenges and Future Perspectives

Felice Crocetto    
Gianluca Russo    
Erika Di Zazzo    
Pasquale Pisapia    
Benito Fabio Mirto    
Alessandro Palmieri    
Francesco Pepe    
Claudio Bellevicine    
Alessandro Russo    
Evelina La Civita    
Daniela Terracciano    
Umberto Malapelle    
Giancarlo Troncone and Biagio Barone    

Resumen

Prostate cancer (PCa) is a widespread malignancy, representing the second leading cause of cancer-related death in men. In the last years, liquid biopsy has emerged as an attractive and promising strategy complementary to invasive tissue biopsy to guide PCa diagnosis, follow-up and treatment response. Liquid biopsy is employed to assess several body fluids biomarkers, including circulating tumor cells (CTCs), extracellular vesicles (EVs), circulating tumor DNA (ctDNA) and RNA (ctRNA). This review dissects recent advancements and future perspectives of liquid biopsy, highlighting its strength and weaknesses in PCa management.

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