Inicio  /  Cancers  /  Vol: 14 Par: 13 (2022)  /  Artículo
ARTÍCULO
TITULO

Phytochemicals for the Prevention and Treatment of Renal Cell Carcinoma: Preclinical and Clinical Evidence and Molecular Mechanisms

Essa M. Bajalia    
Farah B. Azzouz    
Danielle A. Chism    
Derrek M. Giansiracusa    
Carina G. Wong    
Kristina N. Plaskett and Anupam Bishayee    

Resumen

Renal cell carcinoma (RCC) is the most frequently diagnosed kidney cancer. Once RCC metastasizes, successful treatment is difficult to achieve. There is an apparent need for novel approaches to prevent and treat RCC. Phytochemicals are naturally derived compounds gaining increasing scientific interest due to their cancer preventive and chemotherapeutic properties. These phytochemicals have been shown to exhibit a multitude of anticancer effects against RCC. In this systematic review, we critically evaluate the potential these natural compounds possess for the prevention and treatment of RCC and discuss the future implications this may have in the fight against kidney cancer.

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