Inicio  /  Cancers  /  Vol: 15 Par: 14 (2023)  /  Artículo
ARTÍCULO
TITULO

An Integrated CT and MRI Imaging Model to Differentiate between Adrenal Adenomas and Pheochromocytomas

Marta Araujo-Castro    
Iñigo García Sanz    
César Mínguez Ojeda    
María Calatayud    
Felicia A. Hanzu    
Mireia Mora    
Almudena Vicente Delgado    
Concepción Blanco Carrera    
Paz de Miguel Novoa    
María del Carmen López García    
Laura Manjón-Miguélez    
Pablo Rodríguez de Vera Gómez    
María del Castillo Tous    
Rebeca Barahona San Millán    
Mónica Recansens    
Mariana Tomé Fernández-Ladreda    
Nuria Valdés    
Paola Gracia Gimeno    
Cristina Robles Lazaro    
Theodora Michalopoulou    
Victoria Gómez Dos Santos    
Cristina Alvarez-Escola    
Rogelio García Centeno    
Cristina Lamas and Aura Herrera-MartínezaddShow full author listremoveHide full author list    

Resumen

The information obtained in the CT and MRI allows adequate differentiation of adrenal adenomas and pheochromocytomas (PHEOs) with a high diagnostic accuracy. Our study confirms that our predictive model combining tumor size and lipid content has high re-liability for the prediction of PHEO when atypical adrenal lesions are excluded. However, for atypical adrenal lesions with >10 HU in an unenhanced CT scan, MRI information is necessary for a proper exclusion of the PHEO diagnosis. We observed that in the whole cohort (including atypical adenomas), when MRI information was included in the model, the diagnostic accuracy increased to up to 85% when the variables tumor size, high lipid content in an unenhanced CT scan, and hyperintensity in the T2 sequence in MRI were included.

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