Inicio  /  Cancers  /  Vol: 16 Par: 4 (2024)  /  Artículo
ARTÍCULO
TITULO

The Contemporary Role of Hematopoietic Stem Cell Transplantation in the Management of Chronic Myeloid Leukemia: Is It the Same in All Settings?

Ibrahim Elmakaty    
Giuseppe Saglio    
Murtadha Al-Khabori    
Abdelrahman Elsayed    
Basant Elsayed    
Mohamed Elmarasi    
Ahmed Adel Elsabagh    
Awni Alshurafa    
Elrazi Ali and Mohamed Yassin    

Resumen

This review explores the use of hematopoietic stem cell transplantation (HSCT) as a treatment option for chronic myeloid leukemia (CML) patients. While CML treatment has greatly improved with tyrosine kinase inhibitors (TKIs), some patients do not respond well or reach advanced disease stages. The goal now is to achieve treatment-free remission (TFR). Although discontinuing TKIs shows promise, relapse risk is high. This review discusses recent advances in HSCT and its role in CML treatment, suggesting it should be considered early in disease management to enhance the chances of achieving TFR alongside TKIs.

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