Inicio  /  Cancers  /  Vol: 13 Par: 14 (2021)  /  Artículo
ARTÍCULO
TITULO

Correlation of Body Mass Index with Oncologic Outcomes in Colorectal Cancer Patients: A Large Population-Based Study

Chong-Chi Chiu    
Chung-Han Ho    
Chao-Ming Hung    
Chien-Ming Chao    
Chih-Cheng Lai    
Chin-Ming Chen    
Kuang-Ming Liao    
Jhi-Joung Wang    
Yu-Cih Wu    
Hon-Yi Shi    
Po-Huang Lee    
Hui-Ming Lee    
Li-Ren Yeh    
Tien-Chou Soong    
Shyh-Ren Chiang and Kuo-Chen Cheng    

Resumen

Obesity is related to the rising risk of colorectal cancer (CRC). However, the impact of body mass index (BMI) on the oncologic prognosis of CRC patients remains unknown. Conflicting results regarding the relationship between BMI and CRC prognosis have been reported. Therefore, we conducted a nationwide retrospective study that examined the correlation of BMI at diagnosis with overall survival (OS), disease-free survival (DFS), and CRC-specific survival rates in CRC patients. We noted that an underweight status at diagnosis was related to higher mortality and recurrence rates, a decreased rate of OS, and a decreased CRC-specific survival rate compared with those for the normal weight patients. In contrast, overweight and class I or II obese patients had better OS, CRC-specific survival, and DFS rates than those in the normal weight category. Our findings suggest that weight loss in the immediate diagnosis period is unwarranted.

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