Resumen
One in three patients with breast cancer report cancer-related cognitive impairment (CRCI) even before treatment. CRCI can persist and negatively impact patients? quality of life. We used a self-report measure to assess CRCI. We assessed patients? ability to plan and solve everyday life problems, concentrate, and have meaningful relationships with others. We evaluated subgroups of patients with different profiles regarding these abilities and whether they had different demographic and clinical characteristics. Our analyses showed that 64.2%, 43.3%, and 40.1% of the patients had clinically meaningful decrements in their abilities to plan and problem-solve, concentrate, and have meaningful relationships with others, respectively, from prior to through to 6 months after surgery. Pre-surgery symptoms (i.e., anxiety, depression, fatigue, sleep disturbance) and other characteristics (e.g., lower functional status, higher comorbidity) were associated with worse CRCI profiles and may be potential targets for personalized interventions.