Inicio  /  Cancers  /  Vol: 14 Par: 13 (2022)  /  Artículo
ARTÍCULO
TITULO

Development and Validation of a Risk Score for Post-Transplant Lymphoproliferative Disorders among Solid Organ Transplant Recipients

Quenia dos Santos    
Neval Ete Wareham    
Amanda Mocroft    
Allan Rasmussen    
Finn Gustafsson    
Michael Perch    
Søren Schwartz Sørensen    
Oriol Manuel    
Nicolas J. Müller    
Jens Lundgren and Joanne Reekie    

Resumen

Post-transplant lymphoproliferative disease (PTLD) is a well-recognized complication after transplant. We developed and validated a risk score to predict PTLD among solid organ transplant (SOT) recipients. This work presents the first risk score developed and externally validated to predict risk of PTLD among SOT recipients. PTLD is a potentially severe complication after solid organ transplantation, and the best clinical strategy would be to detect the disease at early stages and prevent progression to fulminant lymphoma or even better to predict the risk of a patient developing PTLD prior to onset of disease. Our score had a strong similar discriminatory ability in both derivation and validation cohorts.

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