Resumen
The expression of a variety of microRNAs (miRNAs) and their target genes in gastric cancer is dysregulated and affects the progression of gastric cancer but has not been fully clarified, while bioinformatics is expected to become a method to reveal the relationship and function between them. Thus, through a variety of bioinformatics analyses and experiments, we confirmed that miR-137-3p played a tumor-suppressive role in gastric cancer, and its target gene COL5A1 could reversely sponge miR-137-3p to relieve its targeted inhibition of FSTL1, which may promote the progression of gastric cancer by affecting immune infiltration. These results may provide new ideas for the treatment and future research of gastric cancer.