Resumen
Brain metastases (BM) from colorectal cancer (CRC) are rare. There is little available information regarding incidence, risk factors, prognostic factors, treatment, and overall survival (OS). In this systematic review we performed a research of the current literature and exposed an average incidence of 2.10%. The most-reported risk factors for developing BM were KRAS mutations and lung metastases. The majority of patients with brain metastases did not show neurological symptoms. Treatment options included surgery, radiation, or chemotherapy. While patients who received surgery had prolonged survival, the best survival time was found with a multimodality treatment regimen including neurosurgery.