Inicio  /  Cancers  /  Vol: 16 Par: 4 (2024)  /  Artículo
ARTÍCULO
TITULO

RACK1 Promotes Meningioma Progression by Activation of NF-?B Pathway via Preventing CSNK2B from Ubiquitination Degradation

Ali Abdi Maalim    
Zihan Wang    
Yimin Huang and Ting Lei    

Resumen

Malignant meningiomas have high aggressiveness and recurrence rates and a poor prognosis, with no clear pharmacological treatment available. The study aims to investigate the progression mechanism of malignant meningiomas and the targets of intervention. RACK1 and CSNK2B have been shown to promote tumor progression but their roles in meningiomas are not clear. In this study, we will investigate the roles of RACK1-CSNK2B in meningiomas and search for targets to inhibit the progression of meningiomas.

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