Inicio  /  Cancers  /  Vol: 14 Par: 13 (2022)  /  Artículo
ARTÍCULO
TITULO

Effect of Pre-Existing Sarcopenia on Oncological Outcomes for Oral Cavity Squamous Cell Carcinoma Undergoing Curative Surgery: A Propensity Score-Matched, Nationwide, Population-Based Cohort Study

Yu-Hsiang Tsai    
Wan-Ming Chen    
Ming-Chih Chen    
Ben-Chang Shia    
Szu-Yuan Wu and Chun-Chi Huang    

Resumen

Although sarcopenia during cancer diagnosis is an independent prognostic factor for poor overall survival in patients with various cancers, whether pre-existing sarcopenia is an independent risk factor for oral cavity squamous cell carcinoma (OCSCC) remains unclear. Therefore, we conducted a head-to-head propensity score matching (PSM) study to estimate the oncological outcomes of pre-existing sarcopenia in patients with OCSCC undergoing curative surgery. Both univariate and multivariate Cox regression analyses indicated that pre-existing sarcopenia was associated with poor survival than nonsarcopenia. Old age, male sex, advanced pT, advanced pN, differentiation grade II?III, margin-positive cancer, lymphovascular invasion, and CCI = 1 were significant poor prognostic factors for survival in the patients with OCSCC undergoing curative surgery.

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