Resumen
The Sena Gallica Roman town was settled on the Adriatic coast in the 5th to 4th century BC. The choice of the site was largely influenced by the geomorphological and physiographic conditions near the Misa river mouth. The interactions among climate variation, river dynamics, and marine oscillation determined the anthropic development. At the same time, the new settlement strongly influenced the evolution of this sector in both medieval and in recent times. This work aims to highlight the geological setting and geomorphological evolution of the Senigallia area within the Northern Marche region, taking into account the main scientific literature and new studies to propose a new interpretation of the Holocene history.