Resumen
The aim of the study is to compare the outcomes of implant and synthetic TIGR mesh-based breast reconstructions in breast cancer patients and women, who have higher lifetime risk for breast cancer, with mutated (changed) copy of genes: BRCA1, BRCA2, PALB2 or CHEK2. This study included 170 patients after 232 mastectomies and immediate breast reconstructions. Preoperative chemotherapy was associated with more frequent minor complications, but not major ones, while postoperative chemotherapy was related to more frequent serious postoperative complications. Postoperative radiotherapy was associated with a higher rate of minor complications than no-radiotherapy. Our research found complications to be significantly associated with expander, big- volume breast, mastectomy in breast cancer patients vs risk-reducing mastectomy/prophylactic surgery in women with mutated gene and postoperative chemotherapy. Patients in whom prepectoral (prosthesis is placed above the pectoralis major muscle) surgeries were performed demonstrated shorter hospitalization time, and lower minor complication rates, but similar major complication rates. Implant-based breast reconstruction with the use of synthetic mesh is a safe and effective method of breast restoration, associated with low morbidity and good cosmesis. Nevertheless, further studies are needed to evaluate the benefits of such treatments.