ARTÍCULO
TITULO

The Effect of Silver Nanoparticles on Learning, Memory and Social Interaction in BALB/C Mice

Khaled Greish    
Abdulelah Abdullah Alqahtani    
Abdulla Falah Alotaibi    
Ahmed Mohamed Abdulla    
Aysha Tariq Bukelly    
Fanar Mohammed Alsobyani    
Ghazi Hamad Alharbi    
Israa Saeed Alkiyumi    
Majed Mutlaq Aldawish    
Turki Fahad Alshahrani    
Valeria Pittalà    
Sebastien Taurin and Amer Kamal    

Resumen

Silver Nanoparticles (AgNPs), an epitome of nanotechnology, appear in everyday products such as water filters, printer ink, toothpaste, food packaging and cosmetics mostly due to their bactericidal properties. Given this high level of public exposure, the safety of AgNPs has never been fully established. The unsafe use of AgNPs could pose a real threat, not only to public health but also to economic growth in many industries. In this paper, we tested the effect of AgNPs on memory, learning, social behaviour and motor function of BALB/C mice. Outcomes of the present study suggested an impairment of these functions in AgNPs treated groups. Overall, obtained data support the evidence that the systemic exposure to AgNPs may result in alteration of the cerebral cognition and warrants further consideration on the impact of the AgNPs on human health with respect to their potential neurotoxicity.