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Delphine Bachelet, Marc-André Verner, Monica Neri, Émilie Cordina Duverger, Corinne Charlier, Patrick Arveux, Sami Haddad and Pascal Guénel
Exposure to environmental chemicals with hormonal effects, such as organochlorine compounds (OCs), during developmental periods of breast cells may have an impact on the incidence of breast cancer later in life. However, the assessment of exposure to the...
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Hiroshi Yamazaki, Kana Horiuchi, Ryohji Takano, Taku Nagano, Makiko Shimizu, Masato Kitajima, Norie Murayama and Fumiaki Shono
The present study defined a simplified physiologically based pharmacokinetic (PBPK) model for nicotine and its primary metabolite cotinine in humans, based on metabolic parameters determined in vitro using relevant liver microsomes, coefficients derived ...
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