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Hao Zhu, Wendi Cao, Yicai Huang, Niel A. Karrow and Zhangping Yang
Pyocyanin (PCN) is an extracellular toxin secreted by Pseudomonas aeruginosa (PA), which has redox capacity and disrupts the redox balance of host cells, affecting cell function and leading to cell death. The aim of this experiment was to compare the deg...
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Jinfeng Yang, Yong Soo Kwon, Eun Soo Seong and Myong Jo Kim
Dendrobium loddigesii has long been used in traditional folk medicine. The purpose of this study was to optimize the culture conditions for its protocorm-like bodies (PLBs) and explore their biological activities. The use of an air-lift bioreactor demons...
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Jinnatun Nahar, Vinothini Boopathi, Esrat Jahan Rupa, Muhammad Awais, Anjali Kariyarath Valappil, Md Niaj Morshed, Mohanapriya Murugesan, Reshmi Akter, Dong Uk Yang, Ramya Mathiyalagan, Deok Chun Yang and Seok-Kyu Jung
The family Thymelaeaceae, which includes huge evergreen trees that are sparsely distributed in tropical rainforests, includes the genus Aquilaria. Numerous medical conditions, including inflammation, cancer, and oxidative stress have been traditionally t...
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Amina Yasin, Abdul Rehman Yasin, Muhammad Rizwan Azam, Ali Raza, Robina Nazir and Ridab Adlan Elamin Abdalla
The p53 pathway has been the focus of many researchers in the last few decades owing to its pivotal role as a frontline cancer suppressant protein. It plays a vital role in maintaining cell cycle checkpoints and cell apoptosis in response to a broken DNA...
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Archana Lakshmanan, Balamuralikrishnan Balasubramanian, Viji Maluventhen, Arunkumar Malaisamy, Rathinasamy Baskaran, Wen-Chao Liu and Maruthupandian Arumugam
Fucoidan, a polymer derived from seaweed, poses a broad range of biological applications, and its potential medicinal benefits have been widely studied over the past decade. In this study, fucoidan was extracted from marine macroalga Sargassum ilicifoliu...
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Abdulaziz A. Al-Khedhairy and Rizwan Wahab
The size of nanomaterials influences physicochemical parameters, and variations in the size of nanomaterials can have a significant effect on their biological activities in cells. Due to the potential applicability of nanoparticles (NPs), the current wor...
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Nazia Afroze, Sreepoorna Pramodh, Abdulmajeed G. Almutary, Tahir A. Rizvi, Naushad Rais, Ritu Raina, Md. Faiyazuddin, Abdullah M. Alnuqaydan and Arif Hussain
Kaempferol, a flavonoid, contains a plethora of therapeutic properties and has demonstrated its efficacy against cancer. This study aims to unravel the molecular targets that are being modulated by kaempferol on HeLa cells. Various assays were performed,...
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Mohammed Al-Zharani, Fahd A. Nasr, Ali S. Alqahtani, Mary Anne W. Cordero, Amal A. Alotaibi, Asmatanzeem Bepari, Saud Alarifi, Ali Daoud, Ibrahim O. Barnawi and Haytham M. Daradka
Datura innoxia is an important species of Solanaceae family with several purposes in folk medicine. This study intends to explore the cytotoxic effect of D. innoxia on various cancer cell proliferation. D. innoxia ethanolic extract?s effect on the progre...
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Petra Otevrelová and Barbora Brodská
Survivin is a 16.5 kDa protein highly expressed in centrosomes, where it controls proper sister chromatid separation. In addition to its function in mitosis, survivin is also involved in apoptosis. Overexpression of survivin in many cancer types makes it...
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Zhiping He, Shaozhen Wu, Ju Lin, Ashley Booth, Gary O?Neal Rankin, Ivan Martinez and Yi Charlie Chen
Ovarian cancer is the second most common gynecologic cancer with an estimated 13,940 mortalities across the United States in 2020. Natural polyphenols have been shown to double the survival time of some cancer patients due to their anticancer properties....
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