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Luigi Napolitano, Simona Ippoliti, Peter Fletcher, Martina Caruso, Luigi Cirillo, Roberto Miano, Enrico Finazzi Agrò, Roberto La Rocca, Ferdinando Fusco, Davide Arcaniolo and Luca Orecchia
Bladder cancer (BC) is common worldwide, and has aggressive features and high rates of relapse despite treatments. Approximately 30% of patients present with muscle invasive disease, and therefore, high risk of metastasis. This review provides an overvie...
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Cristina Ramona Novaconi, Robert Onulov, Alina Florina Serb, Eugen Sisu, Nicolae Dinca, Mihai-Cosmin Pascariu and Marius Georgescu
Glycosphingolipids (GSLs) are a glycolipid subtype which plays vital roles in numerous biological processes, cell?cell interactions, as well as oncogenesis and ontogenesis. They are ubiquitous molecules found mostly in cell membranes. Abnormal expression...
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Lichao Sun, Yunyun Dong, Shuang Xu, Xiufang Feng and Xiaole Fan
Epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma (KRAS) are the most common driver genes in non-small cell lung cancer patients. However, frequent gene mutation testing raises a potential risk of cancer metastasis. In our paper, a Mut-SeRe...
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Ehsaneddin Jalilian, Michael Linortner and Andreas Uhl
Collective cell movement is an indication of phenomena such as wound healing, embryonic morphogenesis, cancer invasion, and metastasis. Wound healing is a complicated cellular and biochemical procedure in which skin cells migrate from the wound boundarie...
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Elena Martínez-Fernandez, Ignacio Rojas-Valenzuela, Olga Valenzuela and Ignacio Rojas
The diagnosis of different pathologies and stages of cancer using whole histopathology slide images (WSI) is the gold standard for determining the degree of tissue metastasis. The use of deep learning systems in the field of medical images, especially hi...
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Hyung Min Kim, Chang Wook Jeong, Cheol Kwak, Cheryn Song, Minyong Kang, Seong Il Seo, Jung Kwon Kim, Hakmin Lee, Jinsoo Chung, Eu Chang Hwang, Jae Young Park, In Young Choi and Sung-Hoo Hong
Patients with brain metastasis (BM) have a better prognosis when it is detected early. However, current guidelines recommend brain imaging only when there are central nervous system symptoms or abnormal experimental values. Therefore, metastases are disc...
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Peixia Sun, Shengxiong Lao, Dongyang Du, Jiqiang Peng and Xu Yang
Life-cycle population follow-up data collection is time-consuming and often takes decades. General cohort data studies collect short-to-medium-term data from populations of different age groups. The purpose of constructing a life-cycle simulation method ...
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Andrew Carter, Seth Racey and Stephany Veuger
Iron is a key metal involved in several biological processes such as DNA replication and repair, cellular proliferation and cell cycle regulation. Excess volumes of labile iron are toxic and can lead to the production of ROS (reactive oxygen species) via...
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Denise Toscani, Luisa Craviotto and Nicola Giuliani
The alterations of bone remodeling are typical of multiple myeloma (MM) patients where the uncoupled and unbalanced bone remodeling caused the onset of osteolytic lesions. Moreover, bone metastasis occurs in the majority of patients with breast and prost...
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Takahiro Yamasaki, Issei Saeki, Yurika Kotoh-Yamauchi, Ryo Sasaki, Norikazu Tanabe, Takashi Oono, Takashi Matsuda, Takuro Hisanaga, Toshihiko Matsumoto, Isao Hidaka, Tsuyoshi Ishikawa, Taro Takami, Yutaka Suehiro and Isao Sakaida
Recent success of systemic therapeutic agents, including combination immunotherapy, could promote a change in the treatment strategy in patients with advanced hepatocellular carcinoma (HCC). Although hepatic arterial infusion chemotherapy (HAIC) is a tre...
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