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Ghada Alrabeah, Jonathan C. Knowles and Haralampos Petridis
The improved peri-implant bone response demonstrated when utilizing the platform-switching concept may result from the reduced levels of metal ions released from implant?abutment surfaces to the surrounding tissues. These corrosion products may play a ma...
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Mónica Echeverry-Rendón, Luisa F. Berrio, Sara M. Robledo, Jorge A. Calderón, Juan G. Castaño and Felix Echeverría
Magnesium (Mg) has been explored during the last few decades in the biomedical industry as a biodegradable implant. However, mechanical properties and corrosion resistance are still big concerns for clinical use. Therefore, this study proposes a suitable...
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Franziska Sahm, Ana Jakovljevic, Rainer Bader, Rainer Detsch and Anika Jonitz-Heincke
Bone is a highly dynamic tissue characterized mainly by the interactions of osteoblasts and osteoclasts. When the healing ability of bone regeneration is disturbed, targeted biophysical stimulations such as electrical stimulation are applied. In this stu...
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Christian Voelkner, Issam Assi, Willi Karberg, Regina Lange, Sven Neuber, Christiane A. Helm, Martina Gruening, J. Barbara Nebe, Ingo Barke and Sylvia Speller
Molecular surface gradients can constitute electric field landscapes and serve to control local cell adhesion and migration. Cellular responses to electric field landscapes may allow the discovery of routes to improve osseointegration of implants. Flat m...
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Hun Kim, Yang-Ho Lee, Nam-Kwon Kim and Inn-Kyu Kang
Zirconia, with its excellent mechanical strength and esthetics, has a growing potential for applications in dentistry and orthopedics. However, in order for zirconia to have a high affinity with bone tissue, the bioactivity of the surface must be further...
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Ye-Eun Choi, Jung-Mo Yang and Ju-Hyun Cho
Owing to global population aging, instances of bone metabolic diseases have increased. Consequently, interest in natural and functional plant food products for the prevention and treatment of osteoporosis is also increasing. In this study, we determine t...
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Martina Gruening, Jonathan E. Dawson, Christian Voelkner, Sven Neuber, Katja Fricke, Ursula van Rienen, Sylvia Speller, Christiane A. Helm and J. Barbara Nebe
In medical implantology the human biosystem interacts with the artificial biomaterial. For permanent implants, e.g. titanium, it is of importance that cells immediately accept and occupy the material surface. To get deeper insights into molecular mechani...
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Denise Toscani, Luisa Craviotto and Nicola Giuliani
The alterations of bone remodeling are typical of multiple myeloma (MM) patients where the uncoupled and unbalanced bone remodeling caused the onset of osteolytic lesions. Moreover, bone metastasis occurs in the majority of patients with breast and prost...
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Rosa Mancinelli, Ester Sara Di Filippo, Margherita Tumedei, Mariangela Marrone, Antonella Fontana, Valeria Ettorre, Silvia Giordani, Michele Baldrighi, Giovanna Iezzi, Adriano Piattelli and Stefania Fulle
Equine bone blocks have osteogenic effects promoting bone regeneration with biocompatibility and osteoconductivity capacity. Human dental pulp stem cells (hDPSCs) can differentiate into osteoblasts enhancing biomineralization with such scaffolds. Melaton...
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Hyeonjin Cha, Jaeyoung Lee, Hee Ho Park and Ju Hyun Park
The generation of functional osteoblasts from human somatic cells could provide an alternative means of regenerative therapy for bone disorders such as osteoporosis. In this study, we demonstrated the direct phenotypic conversion of human dermal fibrobla...
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