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Yingcong Huang, Kunal Chaturvedi, Al-Akhir Nayan, Mohammad Hesam Hesamian, Ali Braytee and Mukesh Prasad
Parkinson?s disease (PD) is a chronic brain disorder affecting millions worldwide. It occurs when brain cells that produce dopamine, a chemical controlling movement, die or become damaged. This leads to PD, which causes problems with movement, balance, a...
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Abdulhakeem S. Alamri, Majid Alhomrani, Walaa F. Alsanie, Hussain Alyami, Sonam Shakya, Hamza Habeeballah, Osama Abdulaziz, Abdulwahab Alamri, Heba A. Alkhatabi, Raed I. Felimban, Abdulhameed Abdullah Alhabeeb, Moamen S. Refat and Ahmed Gaber
The drug barbital (Bar) has a strong sedative?hypnotic effect. The intermolecular charge transfer compounds associated with the chemical reactions between Bar and some p acceptors, such as 2,6-dibromoquinone-4-chloroimide (DBQ), tetracyanoquinodimethane ...
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Shu Taira, Akari Ikeda, Shoko Kobayashi, Hitomi Shikano, Ryuzoh Ikeda, Yuko Maejima, Shoichiro Horita, Jun Yokoyama and Kenju Shimomura
We compared four derivatization reagents to analyze catecholamines and amino acids by matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. 2,4,6-Trimethylpyrylium tetrafluoroborate (TMPy), 2,4-diphenyl-pyranylium tetrafluoroborate (DPP-...
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Bárbara Costa, Rita Matos, Irina Amorim, Fátima Gärtner and Nuno Vale
The breast cancer therapies available are insufficient, especially since first-line treatments, such as paclitaxel, result in drug resistance and their toxicity often limits their concentration. Strategies like drug repurposing are beneficial, and novel ...
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Robert Siblerud, Joachim Mutter, Elaine Moore, Johannes Naumann and Harald Walach
Mercury is one of the most toxic elements and causes a multitude of health problems. It is ten times more toxic to neurons than lead. This study was created to determine if mercury could be causing Alzheimer?s disease (AD) by cross referencing the effect...
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Valentina D. Maslova,Roman V. Reshetnikov,Vladimir V. Bezugolov,Igor I. Lyubimov,Andrey V. Golovin
Pág. 98 - 102
An in silico approach was adopted to identify potential cyclooxygenase inhibitors through molecular docking studies. Four potentially active molecules were generated by fusion of dopamine with ibuprofen or ketorolac derivatives. The binding mode of the c...
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Yuxin Bai, Kun Zhang, Ru Xu, Hongtao Liu, Fangxia Guan, Huiwen Luo, Ye Chen and Jingan Li
It is generally accepted that stent implantation is the mainstream therapy in clinics for esophageal cancer in the later period. However, the restenosis caused by tumor cells, epithelial cells, and fibroblasts seriously interferes with the stent medical ...
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Na Wang, Xinlin Diao, Jing Zhang and Ping Kang
In this paper, waterborne epoxy (EP) coatings were modified by the incorporation of synthetic structure (DA/meso-TiO2) to improve the anticorrosion ability of waterborne epoxy coatings for steel structures. Fourier transform infrared spectroscopy (FTIR),...
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Vinod Upadhyay, Zachary Bergseth, Brett Kelly and Dante Battocchi
In this work, the performances of several natural organic inhibitors were investigated in a sol-gel system (applied on the magnesium alloy Mg AZ31B substrate). The inhibitors were quinaldic acid (QDA), betaine (BET), dopamine hydrochloride (DOP), and dia...
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