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Ping Dong, Kuo Li, Ming Wang, Feitao Li, Wei Guo and Haiping Si
In addition to the conventional situation of detecting a single disease on a single leaf in corn leaves, there is a complex phenomenon of multiple diseases overlapping on a single leaf (compound diseases). Current research on corn leaf disease detection ...
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Rayanne H. N. Silva, Emanuel P. Magalhães, Rebeca C. Gomes, Yunierkis Perez-Castillo, Alice M. C. Martins and Damião P. de Sousa
Neglected tropical diseases (NTDs) cause thousands of deaths each year. Among these diseases, we find Chagas disease, whose etiologic agent is Trypanosoma cruzi. Piplartine is an alkamide present in various species of the genus Piper that possess trypano...
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Vasilios Liolios, Dimitrios Kanelis, Chrysoula Tananaki and Maria-Anna Rodopoulou
American Foulbrood (AFB) is a major endemic disease affecting the bee brood and the absence of chemical therapeutic treatments leads beekeepers to develop alternative management plans, based mainly on the prevention and accurate diagnosis of symptoms. On...
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Luciana Rigoli, Valerio Caruso, Concetta Aloi, Alessandro Salina, Mohamad Maghnie, Giuseppe d'Annunzio, Olga Lamacchia, Giuseppina Salzano, Fortunato Lombardo and Giuseppe Picca
Wolfram syndrome 1, a rare autosomal recessive neurodegenerative disease, is caused by mutations in the WFS1 gene. It is characterized by diabetes insipidus, diabetes mellitus, optic atrophy, and deafness (DIDMOAD), and other clinical manifestations such...
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Aulia Fadli, Wisnu Ananta Kusuma, Annisa, Irmanida Batubara and Rudi Heryanto
Coronavirus disease 2019 pandemic spreads rapidly and requires an acceleration in the process of drug discovery. Drug repurposing can help accelerate the drug discovery process by identifying new efficacy for approved drugs, and it is considered an effic...
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Georgia Michailidou, George Z. Papageorgiou and Dimitrios N. Bikiaris
Chronic obstructive pulmonary disease (COPD) is a life-threatening disease of the respiratory system, affecting many patients worldwide. Budesonide (BUD), a synthetic glucocorticosteroid applied for the treatment of COPD patients, is a hydrophobic compou...
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Sadaf Jamal Gilani, May Nasser Bin-Jumah, Syed Sarim Imam, Sultan Alshehri, Mohammed Asadullah Jahangir and Ameeduzzafar Zafar
Rheumatoid arthritis is an autoimmune disease characterized by chronic synovitis that leads to tissue dysfunction as well as loss of complete function. There are several synthetic NSAIDs, glucocorticoids and biological drugs that are commonly used to tre...
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Alexey V. Sulimov,Danil C. Kutov,Vladimir B. Sulimov
Pág. 26 - 50
This review is based on the peer?reviewed research literature including the author?s own publications devoted to supercomputer docking. The general view on docking and its role at the initial stage of the rational drug design is presented. Molecules of m...
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Hue Keat Yung
Pág. 51
Gamavuton-0 (GVT-0) is a new pharmaceutical compound that has proven to treat the inflammatory disease at the joint and cartilage tissue. The study of effect of pH towards the solubility of GVT-0 is importa...
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Daniele Lantagne, Marlene Wolfe, Karin Gallandat and Melissa Opryszko
The scale of the 2014?2017 West African Ebola Virus Disease outbreak overwhelmed the international response capacity. This has led to inconsistencies in international guidance documents, particularly around chlorine disinfection of surfaces and hands to ...
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