ARTÍCULO
TITULO

Predicting Cell Cleavage Timings from Time-Lapse Videos of Human Embryos

Akriti Sharma    
Ayaz Z. Ansari    
Radhika Kakulavarapu    
Mette H. Stensen    
Michael A. Riegler and Hugo L. Hammer    

Resumen

Assisted reproductive technology is used for treating infertility, and its success relies on the quality and viability of embryos chosen for uterine transfer. Currently, embryologists manually assess embryo development, including the time duration between the cell cleavages. This paper introduces a machine learning methodology for automating the computations for the start of cell cleavage stages, in hours post insemination, in time-lapse videos. The methodology detects embryo cells in video frames and predicts the frame with the onset of the cell cleavage stage. Next, the methodology reads hours post insemination from the frame using optical character recognition. Unlike traditional embryo cell detection techniques, our suggested approach eliminates the need for extra image processing tasks such as locating embryos or removing extracellular material (fragmentation). The methodology accurately predicts cell cleavage stages up to five cells. The methodology was also able to detect the morphological structures of later cell cleavage stages, such as morula and blastocyst. It takes about one minute for the methodology to annotate the times of all the cell cleavages in a time-lapse video.

 Artículos similares

       
 
Emily Grise, Anson Stewart, Ahmed El-Geneidy     Pág. 863 - 884
As cities have grown more dispersed and auto-oriented, demand for travel has become increasingly difficult to meet via public transit. Public transit ridership, particularly bus ridership, has recently been on the decline in many urban areas in Canada an... ver más

 
Andriani Skopeliti, Leda Stamou, Lysandros Tsoulos and Shachak Pe?eri    
This paper presents an integrated digital methodology for the generalization of soundings. The input for the sounding generalization procedure is a high resolution Digital Terrain Model (DTM) and the output is a sounding data set appropriate for portraya... ver más

 
The zinc/bromine (Zn/Br2) flow battery is an attractive rechargeable system for grid-scale energy storage because of its inherent chemical simplicity, high degree of electrochemical reversibility at the electrodes, good energy density, and abu... ver más
Revista: Energies

 
Beata Calka and Elzbieta Bielecka    
The issue of population dataset reliability is of particular importance when it comes to broadening the understanding of spatial structure, pattern and configuration of humans? geographical location. The aim of the paper was to estimate the reliability o... ver más

 
Zhigang Han, Fen Qin, Caihui Cui, Yannan Liu, Lingling Wang and Pinde Fu    
A soil erosion model is used to evaluate the conditions of soil erosion and guide agricultural production. Recently, high spatial resolution data have been collected in new ways, such as three-dimensional laser scanning, providing the foundation for refi... ver más