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Inicio  /  Cancers  /  Vol: 15 Par: 9 (2023)  /  Artículo
ARTÍCULO
TITULO

Biomolecules Involved in Both Metastasis and Placenta Accreta Spectrum?Does the Common Pathophysiological Pathway Exist?

Anna K. Rekowska    
Karolina Obuchowska    
Magdalena Bartosik    
Zaneta Kimber-Trojnar    
Magdalena Slodzinska    
Magdalena Wierzchowska-Opoka and Bozena Leszczynska-Gorzelak    

Resumen

Both invasive placentation and cancer metastasis involve the intricate migration and invasion of cells into the surrounding tissues, while also creating new blood vessels to support their growth. The complex interplay of molecular signals that regulate cell behavior, including growth factors, cytokines, and extracellular matrix components, plays a crucial role in both processes. Despite their differing physiological contexts and evolutionary origins, invasive placentation and cancer metastasis share many molecular and cellular mechanisms that allow them to invade and proliferate in the surrounding tissues. In both pathological conditions, cells need to overcome the local mechanisms of immunological defense, activate invasion, and induce angiogenesis. This article focuses on describing the biomolecules that link these pathological processes.

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