Resumen
Cholangiocarcinomas are aggressive tumors that arise from the biliary system. They are highly diverse, both morphologically, in terms of histology and imaging, and biologically in terms of prognosis and response to therapy. Robust predictors of prognosis are critical to ensure that the most effective therapy is allocated to each patient. The presence of a dense, fibrotic stroma within the tumor has already been associated with a poor prognosis in mass-forming intrahepatic cholangiocarcinoma (IMCC). This histologic feature has also been associated with increased retention of gadoxetic acid (Gd-EOB), a liver-specific contrast agent in magnetic resonance imaging (MRI). We investigated whether the IMCC?s signal intensity in the late phase of Gd-EOB-enhanced MRI can non-invasively identify patients who have a relatively worse prognosis.