Redirigiendo al acceso original de articulo en 16 segundos...
Inicio  /  Applied Sciences  /  Vol: 9 Par: 12 (2019)  /  Artículo
ARTÍCULO
TITULO

Molecular Specific and Sensitive Detection of Pyrazinamide and Its Metabolite Pyrazinoic Acid by Means of Surface Enhanced Raman Spectroscopy Employing In Situ Prepared Colloids

Anna Muehlig    
Izabella J. Jahn    
Jan Heidler    
Martin Jahn    
Karina Weber    
Patricia Sheen    
Mirko Zimic    
Dana Cialla-May and Juergen Popp    

Resumen

With the presented microfluidic LoC-SERS device, it is possible to detect simultaneously the prodrug pyrazinamide (PZA) and its metabolite pyrazinoic acid (POA). Thus, our proposed detection scheme could be used for an indirect detection of PZA resistance in Mycobacteria tuberculosis culture supernatants.

 Artículos similares

       
 
Emiliana Pandolfo, Anna Barra Caracciolo and Ludovica Rolando    
Hydrocarbons occur in fossil fuels such as crude oil and consist mainly of hydrogen and carbon. Although they are natural chemicals, crude oil refining results in commercial products with new physico-chemical properties, which can increase their complexi... ver más
Revista: Water

 
Maria Barbara Rózanska, Patrycja Kokolus, Jakub Królak, Patrycja Jankowska, Agata Osos, Magda Romanowska, Lukasz Szala, Przemyslaw Lukasz Kowalczewski, Jacek Lewandowicz, Lukasz Masewicz, Hanna Maria Baranowska and Sylwia Mildner-Szkudlarz    
The present study aimed to evaluate the effect of the extrusion process and particle size on the properties of rice flour (microstructure, pasting properties), gluten-free dough (rheological properties), and bread (texture, specific volume, water absorpt... ver más
Revista: Applied Sciences

 
Divakar Dahiya and Poonam Singh Nigam    
Dextran, a microbial metabolite of diverse molecular configurations, can be biosynthesized employing selected strains of characterized species of bacteria. Dextran molecules are secreted as an extracellular polysaccharide in the culture medium of the bac... ver más
Revista: Applied Sciences

 
Xuyi Zhang, Yang Bai, Yuan Ma, Peidong He, Yinhui Tang and Xiaoning Lv    
Raman spectroscopy has been widely applied in numerous fields including bioanalysis, disease diagnosis, and molecular recognition, owing to its unique advantages of being non-invasive, rapid, and highly specific. However, the acquisition of Raman spectra... ver más
Revista: Applied Sciences

 
Pathik Sahoo    
Multistep flow catalytic reactions in organic chemistry integrate multiple sequential organic reactions to enhance cost-efficiency, time management, and labour resources, all while boosting effectiveness and environmental sustainability. Similar to how w... ver más
Revista: ChemEngineering