Resumen
Cancer is the leading cause of death globally, prompting extensive research into drugs that can enhance survival rates. The aim of our review was to assess the potential of asiatic acid as an anticancer drug, or as a support for existing cancer therapies. In vitro and in vivo studies have shown that asiatic acid activates various molecular pathways and exerts multidirectional effects in an organism. It has been confirmed that metabolic pathways regulated by molecular targets, e.g., TNF-a, NF-?B, PI3K/Akt, VEGF, and others, are affected by asiatic acid and are crucial in tumorigenesis, proliferation, and metastasis. In cancer cells, asiatic acid can decrease gene expression, reduce phosphorylation, and induce apoptosis. The gathered evidence suggests that asiatic acid warrants further investigation as a potential anticancer drug or adjunctive therapy.