Resumen
Five-year overall survival in patients with epithelial ovarian cancer is still set at 50%, going down to 31% in patients presenting with advanced stage disease. Recent studies have shown associations between some body composition values, such as sarcopenia, and overall survival in ovarian cancer patients, but the results are still conflicting. The main aim of this retrospective exploratory study was to assess the associations between many body composition components, extracted from computed tomography performed in routine clinical practice, and overall survival and progression-free survival. Extended body composition evaluation confirmed an association between body composition components (skeletal muscle volume) and overall survival and progression-free survival, as well as associations between intramuscular adipose tissue, epicardial adipose tissue and paracardial adipose tissue with progression-free survival. These promising results encourage further studies assessing the role of body composition in outcomes of ovarian cancer patients.