Resumen
Prostate cancer is one of the leading causes of cancer-related deaths among men in the United States and Europe. While conventional treatment options either have high toxicity profiles or are limited by the tumor?s ability to develop resistance, immunotherapy is specific in targeting malignant cells. It can also enable the immune system to adapt dynamically while the tumor evades the destruction process. Cellular Immunotherapy in particular is a promising approach; however, there are gaps in knowledge in the current literature on its application. To contribute to a wider understanding of cellular immunotherapy, specifically focusing on the chimeric antigen receptors (CAR) T-cells, their benefits and application in clinical settings, we conducted a comprehensive systematic review.