Resumen
Genetic information is essential before starting the treatment of advanced-stage non-small-cell lung cancer (NSCLC) and in the adjuvant setting (EGFR mutation status only) after pulmonary resection of early-stage NSCLC. Several genetic tests for NSCLC are available, which vary in turnaround time and cost (usually higher costs for multi-gene tests). The Idylla? EGFR Mutation Test is an ultra-rapid single-gene test used to detect EGFR mutations. In this study, we compared the performance of the Idylla EGFR Mutation Test with the current standard EGFR single-gene test (Cobas® EGFR Mutation Test v2) and demonstrate the accuracy of the Idylla EGFR Mutation Test as a molecular screening platform. From these data, we propose genetic testing strategies that may reduce the costs and shorten the turnaround time in advanced-stage NSCLC and in the adjuvant setting after pulmonary resection of early-stage NSCLC.