Inicio  /  Applied Sciences  /  Vol: 10 Par: 24 (2020)  /  Artículo
ARTÍCULO
TITULO

Radiotherapy of Conjunctival Melanoma: Role and Challenges of Brachytherapy, Photon-Beam and Protontherapy

Corrado Spatola    
Rocco Luca Emanuele Liardo    
Roberto Milazzotto    
Luigi Raffaele    
Vincenzo Salamone    
Antonio Basile    
Pietro Valerio Foti    
Stefano Palmucci    
Giuseppe Antonio Pablo Cirrone    
Giacomo Cuttone    
Andrea Russo    
Teresio Avitabile    
Michele Reibaldi    
Antonio Longo    
Giuseppe Broggi    
Vincenza Bonfiglio    
Rosario Caltabiano    
Stefano Pergolizzi and Floriana Arena    

Resumen

Conjunctival melanoma is a rare neoplasia, whose therapeutic management is generally of ophthalmological relevance, through radical surgical resection. The high incidence of local relapses after surgery, has made it necessary to combine various types of adjuvant treatments, which in some cases take on the role of radical treatments. Among these non-surgical treatments, those involving the application of ionizing radiation are becoming particularly important. In this review, we discuss the role of episcleral brachytherapy, external photon-beam radiotherapy, also made through stereotactic or radiosurgical modality, and of proton-beam radiotherapy. We try also to take stock of the benefits of the different irradiation modalities and the application difficulties of each.