Resumen
Laser irradiation of noble metal nanoparticles has recently been investigated to achieve a potential clinically relevant photothermal effect. This work presents the first study of gold nanorods (GNRs)-assisted therapy of a pancreas tumor using the Monte Carlo-based code developed with Geant4 Application for Emission Tomography (GATE). Having the possibility of setting the optical and thermal properties of nanoparticles, GATE platform allows for the modeling of the GNRs-mediated hyperthermia therapy as well as heat diffusion in tissue. The code was benchmarked to validate the heat distribution between the simulation and the experiment.