Resumen
Performing this real-world analysis, we intended to see if postoperative (adjuvant) systemic treatment outcomes in a Polish melanoma patient population are comparable to the results from international trials based on which the treatment was registered worldwide. We intended to provide evidence on the efficacy and safety of postoperative melanoma treatment from everyday practice. We have shown that the type of surgical procedure on the lymph nodes prior to adjuvant treatment does not influence the outcome of that treatment. Our results support a de-escalation of surgery approach in melanoma patients. We support the value of adjuvant treatment for melanoma patients selected according to new guidelines implemented in parallel to the registration process. Analyzing the recorded side effects of adjuvant systemic treatment in our group of patients, we have noticed that severe complications worsen survival, giving us an indication not to treat by all means despite toxicity, particularly since it is a complementary to surgery treatment.