Inicio  /  Cancers  /  Vol: 13 Par: 20 (2021)  /  Artículo
ARTÍCULO
TITULO

Prospective Evaluation over 15 Years of Six Breast Cancer Risk Models

Sherly X. Li    
Roger L. Milne    
Tú Nguyen-Dumont    
Dallas R. English    
Graham G. Giles    
Melissa C. Southey    
Antonis C. Antoniou    
Andrew Lee    
Ingrid Winship    
John L. Hopper    
Mary Beth Terry and Robert J. MacInnis    

Resumen

Australia has one of the world?s highest breast cancer incidences. For most women who are not classified as at high risk, eligibility and frequency of breast cancer screening in Australia is based solely on their age. Breast cancer risk models can help to optimise early detection and management of breast cancer. We evaluated six commonly used models over 15 years follow-up using an Australian community-based cohort of 7608 women aged 50?65 years. The BOADICEA and IBIS models best discriminated women who were at higher risk of developing breast cancer from those at lower risk, but no model apart from BOADICEA accurately predicted absolute risk across the risk spectrum. The BOADICEA model could be of clinical use for women of similar demography.

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