Inicio  /  Cancers  /  Vol: 12 Par: 11 (2020)  /  Artículo
ARTÍCULO
TITULO

Outcome After 68Ga-PSMA-11 versus Choline PET-Based Salvage Radiotherapy in Patients with Biochemical Recurrence of Prostate Cancer: A Matched-Pair Analysis

Nina-Sophie Schmidt Hegemann    
Paul Rogowski    
Chukwuka Eze    
Christian Schäfer    
Christian Stief    
Sebastian Lang    
Simon Spohn    
Rieke Steffens    
Minglun Li    
Christian Gratzke    
Wolfgang Schultze-Seemann    
Harun Ilhan    
Wolfgang Peter Fendler    
Peter Bartenstein    
Ute Ganswindt    
Alexander Buchner    
Anca-Ligia Grosu    
Claus Belka    
Philipp Tobias Meyer    
Simon Kirste and Constantinos Zamboglouadd Show full author list remove Hide full author list    

Resumen

In this bi-institutional analysis including 421 patients, we report an overall high biochemical-recurrence free survival rate (58% after three years) after positron-emission tomography (PET)-based salvage radiotherapy (sRT). Additionally, the strong prognostic effect of prostate specific antigen (PSA) level prior to sRT in this patient cohort was observed in multivariate regression analyses. Finally, patients who received staging with two different PET tracers for sRT guidance (cholin vs. prostate specific membrane antigen (PSMA) PET) were compared via propensity score matching and no significant differences in biochemical-recurrent free survival BRFS between the two tracers were observed.

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