Inicio  /  Cancers  /  Vol: 15 Par: 9 (2023)  /  Artículo
ARTÍCULO
TITULO

The Cross Talk between Cellular Senescence and Melanoma: From Molecular Pathogenesis to Target Therapies

Jiahua Liu    
Runzi Zheng    
Yanghuan Zhang    
Shuting Jia    
Yonghan He and Jing Liu    

Resumen

Melanoma is a dreadful type of skin cancer with a poor response to therapy. Senescent cells have been found to accumulate with age and may contribute to the occurrence and development of melanoma. This review aims to provide an overview of skin aging and melanoma, including the molecular mechanisms, microenvironmental factors, and therapeutic strategies. In addition, some potential common targets between melanoma and cell senescence will be also discussed.

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