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Daniela Galatro, Rosario Trigo-Ferre, Allana Nakashook-Zettler, Vincenzo Costanzo-Alvarez, Melanie Jeffrey, Maria Jacome, Jason Bazylak and Cristina H. Amon
Acute myeloid leukemia (AML) is a type of blood cancer that affects both adults and children. Benzene exposure has been reported to increase the risk of developing AML in children. The assessment of the potential relationship between environmental benzen...
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Petra Otevrelová and Barbora Brodská
Survivin is a 16.5 kDa protein highly expressed in centrosomes, where it controls proper sister chromatid separation. In addition to its function in mitosis, survivin is also involved in apoptosis. Overexpression of survivin in many cancer types makes it...
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Joaquim Carreras, Yara Y. Kikuti, Masashi Miyaoka, Shinichiro Hiraiwa, Sakura Tomita, Haruka Ikoma, Yusuke Kondo, Atsushi Ito, Sawako Shiraiwa, Rifat Hamoudi, Kiyoshi Ando and Naoya Nakamura
Objective: We have recently identified using multilayer perceptron analysis (artificial intelligence) a set of 25 genes with prognostic relevance in diffuse large B-cell lymphoma (DLBCL), but the importance of this set in other hematological neoplasia re...
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Rashmi Kanagal-Shamanna, Weiqiang Zhao, Saroj Vadhan-Raj, Martin H. Nguyen, Michael H. Fernandez, L. Jeffrey Medeiros and Carlos E. Bueso-Ramos
Environmental exposure to benzene occurs through cigarette smoke, unleaded gasoline and certain types of plastic. Benzene is converted to hematotoxic metabolites by the hepatic phase-I enzyme CYP2E1, and these metabolites are detoxified by the phase-II e...
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