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Krzysztof Wojciech Fornalski
Every living organism is a physical, complex system which can be modeled by nonlinear dynamical equations in some very narrowed cases. Here we discuss the adoption and potential application of Lotka?Volterra equations (with damping) to simulate, on a ver...
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Nazia Afroze, Sreepoorna Pramodh, Abdulmajeed G. Almutary, Tahir A. Rizvi, Naushad Rais, Ritu Raina, Md. Faiyazuddin, Abdullah M. Alnuqaydan and Arif Hussain
Kaempferol, a flavonoid, contains a plethora of therapeutic properties and has demonstrated its efficacy against cancer. This study aims to unravel the molecular targets that are being modulated by kaempferol on HeLa cells. Various assays were performed,...
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Giuseppe Genchi, Graziantonio Lauria, Alessia Catalano, Alessia Carocci and Maria Stefania Sinicropi
Arsenic intoxication represents a worldwide health problem and occurs mainly through drinking water. Arsenic, a metalloid and naturally occurring element, is one of the most abundant elements in the earth?s crust, whose toxicity depends on the reduction ...
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Muhammad Nadeem, Muhammad Imran, Tanweer Aslam Gondal, Ali Imran, Muhammad Shahbaz, Rai Muhammad Amir, Muhammad Wasim Sajid, Tahira Batool Qaisrani, Muhammad Atif, Ghulam Hussain, Bahare Salehi, Elise Adrian Ostrander, Miquel Martorell, Javad Sharifi-Rad, William C. Cho and Natália Martins
Naturally occurring food-derived active ingredients have received huge attention for their chemopreventive and chemotherapy capabilities in several diseases. Rosmarinic acid (RA) is a caffeic acid ester and a naturally-occurring phenolic compound in a nu...
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Ernesto Burgio, Prisco Piscitelli and Annamaria Colao
The dominant pathogenic model, somatic mutation theory (SMT), considers carcinogenesis as a ?genetic accident? due to the accumulation of ?stochastic? DNA mutations. This model was proposed and accepted by the scientific community when cancer mainly affe...
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Alexandra Iulia Irimie, Cornelia Braicu, Roxana Cojocneanu, Lorand Magdo, Anca Onaciu, Cristina Ciocan, Nikolay Mehterov, Diana Dudea, Smaranda Buduru and Ioana Berindan-Neagoe
Smoking is a well-known behavior that has an important negative impact on human health, and is considered to be a significant factor related to the development and progression of head and neck squamous cell carcinomas (HNSCCs). Use of high-dimensional da...
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Demetrios Petrakis, Loukia Vassilopoulou, Charalampos Mamoulakis, Christos Psycharakis, Aliki Anifantaki, Stavros Sifakis, Anca Oana Docea, John Tsiaoussis, Antonios Makrigiannakis and Aristides M. Tsatsakis
The review aims to comprehensively present the impact of exposure to endocrine disruptors (EDs) in relation to the clinical manifestation of obesity and related diseases, including diabetes mellitus, metabolic syndrome, cardiovascular diseases, carcinoge...
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Yue Wang, Hong Gao, Xiao-Lin Na, Shu-Ying Dong, Hong-Wei Dong, Jia Yu, Li Jia and Yong-Hui Wu
The toxicity and carcinogenicity of aniline in humans and animals have been well documented. However, the molecular mechanism involved in aniline-induced liver toxicity and carcinogenesis remains unclear. In our research, primary cultured hepatocytes wer...
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Michael Goodman, Judy S. LaKind, Jerald A. Fagliano, Timothy L. Lash, Joseph L. Wiemels, Deborah M. Winn, Chirag Patel, Juliet Van Eenwyk, Betsy A. Kohler, Enrique F. Schisterman, Paul Albert and Donald R. Mattison
Residential clusters of non-communicable diseases are a source of enduring public concern, and at times, controversy. Many clusters reported to public health agencies by concerned citizens are accompanied by expectations that investigations will uncover ...
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