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Xuejian Han and Manzhou Zhang
A beam-expanding method that can achieve uniform proton beams for FLASH therapy is provided.
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Martin Farkas, Benedikt Bergmann, Pavel Broulim, Petr Burian, Giovanni Ambrosi, Philipp Azzarello, Luká? Pu?man, Mateusz Sitarz, Petr Smolyanskiy, Daniil Sukhonos and Xin Wu
We present the characterization of a highly segmented ?large area? hybrid pixel detector (Timepix3, 512 × 512 pixels, pixel pitch 55 µm) for application in space experiments. We demonstrate that the nominal power consumption of 6 W can be reduced by chan...
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Isabelle Schilling, Claus Maximilian Bäcker, Christian Bäumer, Carina Behrends, Marius Hötting, Jana Hohmann, Kevin Kröninger, Beate Timmermann and Jens Weingarten
The accurate measurement of the beam range in the frame of quality assurance (QA) is a requirement for clinical use of a proton therapy machine. Conventionally used detectors mostly estimate the range by measuring the depth dose distribution of the proto...
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Md. Rafiqul Islam, Mehrdad Shahmohammadi Beni, Shigeki Ito, Shinichi Gotoh, Taiga Yamaya and Hiroshi Watabe
Proton range monitoring and verification is important to enhance the effectiveness of treatment by ensuring that the correct dose is delivered to the correct location. Upon proton irradiation, different positron emitting radioisotopes are produced by the...
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César Jesús-Valls, Marc Granado-González, Thorsten Lux, Tony Price and Federico Sánchez
Recently, we proposed a novel range detector concept named ASTRA. ASTRA is optimized to accurately measure (better than 1%) the residual energy of protons with kinetic energies in the range from tens to a few hundred MeVs at a very high rate of O(" role=...
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Johannes Leidner, Fabrizio Murtas and Marco Silari
The GEMPix is a small gaseous detector with a highly pixelated readout, consisting of a drift region, three Gas Electron Multipliers (GEMs) for signal amplification, and four Timepix ASICs with 55 µm pixel pitch and a total of 262,144 pixels. A continuou...
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Elia Arturo Vallicelli and Marcello De Matteis
This paper analyzes how to improve the precision of ionoacoustic proton range verification by optimizing the analog signal processing stages with particular emphasis on analog filters. The ionoacoustic technique allows one to spatially detect the proton ...
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Saverio Braccini, Tommaso S. Carzaniga, Giulia Pisegna and Paola Scampoli
The possibility of performing proton radiography by using the proton angular spread due to Coulomb multiple scattering was investigated, for the first time, with an emulsion film detector. Two different phantoms were irradiated with the therapeutic proto...
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Andrew K.H. Robertson, Andrew Lobbezoo, Louis Moskven, Paul Schaffer and Cornelia Hoehr
With recent impressive clinical results of targeted alpha therapy using 225Ac, significant effort has been directed towards providing a reliable and sufficient supply of 225Ac to enable widespread using of 225Ac-radiopharmaceuticals. TRIUMF has begun pro...
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Roland Schnuerer, Jacinta Yap, Hao Zhang, Tomasz Cybulski, Tony Smith, Guido Haefeli, Olivier Girard, Tomasz Szumlak and Carsten Welsch
Knowledge of the beam properties in proton therapy through beam monitoring is essential, ensuring an effective dose delivery to the patient. In clinical practice, currently used interceptive ionisation chambers require daily calibration and suffer from a...
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