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Luana Conte, Emanuele Rizzo, Tiziana Grassi, Francesco Bagordo, Elisabetta De Matteis and Giorgio De Nunzio
Pedigree charts remain essential in oncological genetic counseling for identifying individuals with an increased risk of developing hereditary tumors. However, this valuable data source often remains confined to paper files, going unused. We propose a co...
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Giuseppe Agapito and Mario Cannataro
Technological advances in high throughput platforms for biological systems enable the cost-efficient production of massive amounts of data, leading life science to the Big Data era. The availability of Big Data provides new opportunities and challenges f...
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Santiago Timón-Reina, Mariano Rincón, Rafael Martínez-Tomás, Bjørn-Eivind Kirsebom and Tormod Fladby
Applying knowledge graphs, graph analytics, and graph machine learning for integrating multi-modal dementia research data.
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Michaela Cellina, Maurizio Cè, Marco Alì, Giovanni Irmici, Simona Ibba, Elena Caloro, Deborah Fazzini, Giancarlo Oliva and Sergio Papa
Digital twins are virtual replicas of physical objects or systems. This new technology is increasingly being adopted in industry to improve the monitoring and efficiency of products and organizations. In healthcare, digital human twins (DHTs) represent v...
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Nermin Abdelhakim Othman, Manal A. Abdel-Fattah and Ahlam Talaat Ali
Because of technological advancements and their use in the medical area, many new methods and strategies have been developed to address complex real-life challenges. Breast cancer, a particular kind of tumor that arises in breast cells, is one of the mos...
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Intan Filzah Mahmod, Saharshini Jeyasimman, Muhamad Shakirin Mispan, Farahaniza Supandi, Alfi Khatib and Mohd Zuwairi Saiman
Weedy rice (Oryza spp.) is a notorious weed that invades paddy fields and hampers the rice?s production and yield quality; thus, it has become a major problem for rice farmers worldwide. Weedy rice comprises a diverse morphology and phenotypic variation;...
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Laura Madrid-Márquez, Cristina Rubio-Escudero, Beatriz Pontes, Antonio González-Pérez, José C. Riquelme and Maria E. Sáez
Background and Objectives: The burst of high-throughput omics technologies has given rise to a new era in systems biology, offering an unprecedented scenario for deriving meaningful biological knowledge through the integration of different layers of info...
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Changwon Yoo, Efrain Gonzalez, Zhenghua Gong and Deodutta Roy
Every year, biomedical data is increasing at an alarming rate and is being collected from many different sources, such as hospitals (clinical Big Data), laboratories (genomic and proteomic Big Data), and the internet (online Big Data). This article prese...
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Jinyang Liu, Yun Lin, Jinbin Chen, Chenchen Xue, Ranran Wu, Qiang Yan, Xin Chen and Xingxing Yuan
Heterosis has been utilized in crops for a long time, and although crop fertility is the basis for the utilization of heterosis, there is limited information concerning the genic male sterility (GMS) of mungbean. Therefore, based on the genic male steril...
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Fabio Cumbo, Eleonora Cappelli and Emanuel Weitschek
The recent advancements in cancer genomics have put under the spotlight DNA methylation, a genetic modification that regulates the functioning of the genome and whose modifications have an important role in tumorigenesis and tumor-suppression. Because of...
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