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Rejane Viana, Ana C. Rocha, André P. Sousa, Diogo Ferreira, Rúben Fernandes, Cátia Almeida, Patrick J. Pais, Pilar Baylina and Ana Cláudia Pereira
Colorectal cancer (CRC) is the third most common cancer diagnosed today and the third leading cause of death among cancer types. CRC is one of the gastrointestinal tumors with obesity as the main extrinsic risk factor, since, according to authors, the me...
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Enrica Serretiello, Annafrancesca Smimmo, Andrea Ballini, Domenico Parmeggiani, Massimo Agresti, Paola Bassi, Giancarlo Moccia, Antonella Sciarra, Alessandra De Angelis, Paola Della Monica, Maria Michela Marino and Marina Di Domenico
Breast cancer (BC) caused 685,000 deaths globally in 2020, earning the title of the most common type of tumor among females. With a multifactorial genesis, BC is influenced by several factors such as age, genetic and epigenetic predisposition, and an ind...
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Julia Figueroa-Martínez, Dulcenombre M. Saz-Navarro, Aurelio López-Fernández, Domingo S. Rodríguez-Baena and Francisco A. Gómez-Vela
Gene networks have become a powerful tool for the comprehensive examination of gene expression patterns. Thanks to these networks generated by means of inference algorithms, it is possible to study different biological processes and even identify new bio...
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Md Rezaul Hoque Khan, Atiqul Alam Chowdhury, Mohammad Rakibul Islam, Md Sanowar Hosen, Mhamud Hasan Mim and Mirza Muntasir Nishat
For the quick identification of diverse types of cancer/malignant cells in the human body, a new hollow-core optical waveguide based on Photonic Crystal Fiber (PCF) is proposed and numerically studied. The refractive index (RI) differs between normal and...
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Zhanlin Ji, Dashuang Yao, Rui Chen, Tao Lyu, Qinping Liao, Li Zhao and Ivan Ganchev
Mutated cells may constitute a source of cancer. As an effective approach to quantifying the extent of cancer, cell image segmentation is of particular importance for understanding the mechanism of the disease, observing the degree of cancer cell lesions...
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Kristina Vukovic Ðerfi, Tea Vasiljevic and Tanja Matijevic Glavan
Head and neck squamous cell carcinoma (HNSCC) is a very heterogeneous cancer with a poor overall response to therapy. One of the reasons for this therapy resistance could be cancer stem cells (CSCs), a small population of cancer cells with self-renewal a...
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Gloria Perazzoli, Carolina de los Reyes, Cristina Pinedo-Rivilla, Rosa Durán-Patrón, Josefina Aleu, Laura Cabeza, Consolación Melguizo and Jose Prados
The marine environment is a promising source of natural products with possible pharmacological applications. In this sense, marine microorganisms, especially marine fungi, can produce bioactive compounds with various therapeutic properties. Colorectal ca...
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Cristina Ramona Novaconi, Robert Onulov, Alina Florina Serb, Eugen Sisu, Nicolae Dinca, Mihai-Cosmin Pascariu and Marius Georgescu
Glycosphingolipids (GSLs) are a glycolipid subtype which plays vital roles in numerous biological processes, cell?cell interactions, as well as oncogenesis and ontogenesis. They are ubiquitous molecules found mostly in cell membranes. Abnormal expression...
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Ruta Palep?iene, Martynas Maciulevicius, Paulius Ruzgys, Baltramiejus Jak?tys and Saulius ?atkauskas
Gene electrotransfer (GET) is recognized as a promising technique for the development of an efficient tool for gene therapy. Such a therapy would have applications in the treatment of a variety of genetic diseases, including cancer. However, despite its ...
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Laura Orellana
At the very deepest molecular level, the mechanisms of life depend on the operation of proteins, the so-called ?workhorses? of the cell. Proteins are nanoscale machines that transform energy into useful cellular work, such as ion or nutrient transport, i...
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