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Barbara Gawronska-Kozak
The forkhead box N1 (Foxn1) transcription factor regulates biological processes of the thymus and skin. Loss-of-function mutations in Foxn1 cause the nude phenotype in humans, mice, and rats, which is characterized by hairless skin and a lack of thymus. ...
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Jun Song, Brooke Pallas, Dongshan Yang, Jifeng Zhang, Yash Agarwal, Y. Eugene Chen, Moses Bility and Jie Xu
Production of immunodeficient (ID) models in non-murine animal species had been extremely challenging until the advent of gene-editing tools: first zinc finger nuclease (ZFN), then transcription activator-like effector nuclease (TALEN), and most recently...
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