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Sufyan Danish, Asfandyar Khan, L. Minh Dang, Mohammed Alonazi, Sultan Alanazi, Hyoung-Kyu Song and Hyeonjoon Moon
Bioinformatics and genomics are driving a healthcare revolution, particularly in the domain of drug discovery for anticancer peptides (ACPs). The integration of artificial intelligence (AI) has transformed healthcare, enabling personalized and immersive ...
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Kalidoss Rajendran, Ponmurugan Karuppiah, Ponmurugan Ponnusamy, Mohammed Rafi Shaik, Mujeeb Khan, Tae Hwan Oh and Baji Shaik
Thousands of different kinds of lichen metabolites are being examined for their biological activities, including anticancer properties. In this context, the present study aims to assess the anti-inflammatory activity of the acetone extract of Parmotrema ...
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Laura Mosca, Francesca Vitiello, Martina Pagano, Alessandra Coppola, Roberta Veglia Tranchese, Roberta Grillo, Giovanna Cacciapuoti and Marina Porcelli
Squamous cell carcinoma of the head and neck (HNSCC), which includes cancers of the oral cavity and larynx, is one of the most common and highly aggressive malignancies worldwide, despite significant efforts committed in recent decades in its detection, ...
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Daniele Pergolini, Andrea Botticelli, Roberta Fascetti, Federica Rocchetti, Alessio Cirillo, Gianluca Tenore, Gaspare Palaia, Antonella Polimeni and Umberto Romeo
Introduction: Immune Checkpoint Inhibitor (ICI) drugs have led to a revolution in the treatment of different forms of cancer, shifting the target of action from cancer cells to the patient?s immune system, enhancing their responses against the tumor itse...
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Jadwiga Nowak, Anna K. Kiss, Charles Wambebe, Esther Katuura and Lukasz Kuzma
Due to the presence of phytochemicals, plants have been known to be used in the treatment and management of various diseases. Vernonia amygdalina, belonging to the Asteraceae family, is a plant known for its many applications in traditional medicine for ...
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Myung Chul Lee, Shambhavi Pandey, Jae Woon Lim, Sangbae Park, Jae Eun Kim, Hyunmok Son, Jinsub Han, Hoon Seonwoo, Pankaj Garg and Jong Hoon Chung
Cisplatin, a representative anticancer drug used to treat cancer, has many adverse effects. In particular, it causes significant damage to the kidneys. Thus, many researchers have studied the delivery of drugs, such as cisplatin, to cancer areas using ta...
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Zhiping He, Shaozhen Wu, Ju Lin, Ashley Booth, Gary O?Neal Rankin, Ivan Martinez and Yi Charlie Chen
Ovarian cancer is the second most common gynecologic cancer with an estimated 13,940 mortalities across the United States in 2020. Natural polyphenols have been shown to double the survival time of some cancer patients due to their anticancer properties....
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Muhammad Nadeem, Muhammad Imran, Tanweer Aslam Gondal, Ali Imran, Muhammad Shahbaz, Rai Muhammad Amir, Muhammad Wasim Sajid, Tahira Batool Qaisrani, Muhammad Atif, Ghulam Hussain, Bahare Salehi, Elise Adrian Ostrander, Miquel Martorell, Javad Sharifi-Rad, William C. Cho and Natália Martins
Naturally occurring food-derived active ingredients have received huge attention for their chemopreventive and chemotherapy capabilities in several diseases. Rosmarinic acid (RA) is a caffeic acid ester and a naturally-occurring phenolic compound in a nu...
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Gayla L. Poling, Brittany Vlosich and Laura E. Dreisbach
Hundreds of medications commonly prescribed for anticancer treatments and some infections are known to cause hearing damage, referred to as ototoxicity. Preventing or minimizing ototoxicity is critical in order to preserve quality of life for patients re...
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Ill-Min Chung, Govindasamy Rajakumar, Umadevi Subramanian, Baskar Venkidasamy and Muthu Thiruvengadam
Gymnema sylvestre is a plant that is enriched in bioactive compounds. In particular, gymnemic acids (GA) and phenolic compounds (PC) are pharmaceutically important. There is a commercial demand for naturally occurring bioactive compounds, but their avail...
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