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A. Khuzaim Alzahrani, Ahmed A. Alsheikhy, Tawfeeq Shawly, Ahmed Azzahrani and Yahia Said
Blood cancer occurs due to changes in white blood cells (WBCs). These changes are known as leukemia. Leukemia occurs mostly in children and affects their tissues or plasma. However, it could occur in adults. This disease becomes fatal and causes death if...
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Daniela Galatro, Rosario Trigo-Ferre, Allana Nakashook-Zettler, Vincenzo Costanzo-Alvarez, Melanie Jeffrey, Maria Jacome, Jason Bazylak and Cristina H. Amon
Acute myeloid leukemia (AML) is a type of blood cancer that affects both adults and children. Benzene exposure has been reported to increase the risk of developing AML in children. The assessment of the potential relationship between environmental benzen...
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Natalia V. Dobryakova, Dmitry D. Zhdanov, Nikolay N. Sokolov, Svetlana S. Aleksandrova, Marina V. Pokrovskaya and Elena V. Kudryashova
L-asparaginase Rhodospirillum rubrum (RrA) is an enzyme (amidohydrolases; EC 3.5.1.1) that catalyzes the L-asparagine hydrolysis reaction to form L-aspartic acid. Due to the shortcomings of existing L-asparaginases from Esherichia coli (EcA) and Erwinia ...
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Mohamad Abou Ali, Fadi Dornaika and Ignacio Arganda-Carreras
Deep learning (DL) has made significant advances in computer vision with the advent of vision transformers (ViTs). Unlike convolutional neural networks (CNNs), ViTs use self-attention to extract both local and global features from image data, and then ap...
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Yúri Faro Dantas de Sant?Anna, José Elwyslan Maurício de Oliveira and Daniel Oliveira Dantas
The lymphocyte classification problem is usually solved by deep learning approaches based on convolutional neural networks with multiple layers. However, these techniques require specific hardware and long training times. This work proposes a lightweight...
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Kyeong-Hun Choi, Jonghyo Hong, Ki-Young Kim, Hangeun Kim, Sanghyun Lee, Yunji Lee and Dae-Kyun Chung
Inflammation plays an important role in the pathogenesis of metabolic syndrome, which increases the risk of heart disease, stroke, type 2 diabetes, atherosclerosis, non-alcoholic fatty liver disease (NAFLD), and obesity. Here, we produced potent anti-inf...
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Haya I. Aljohar, Abdulmajeed A. Alghamdi, Nasr Y. Khalil, Hany W. Darwish, Rashad Al-Salahi and Ibrahim A. Darwish
The Food and Drug Administration (FDA) has approved duvelisib (DUV) for managing follicular lymphoma, small lymphocytic lymphoma, and relapsed or refractory chronic lymphocytic leukemia. Seliciclib (SEL) is a candidate drug for these cancers, neurodegene...
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Petra Otevrelová and Barbora Brodská
Survivin is a 16.5 kDa protein highly expressed in centrosomes, where it controls proper sister chromatid separation. In addition to its function in mitosis, survivin is also involved in apoptosis. Overexpression of survivin in many cancer types makes it...
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Jozef Hudec, Jan Mojzis, Marta Habanova, Jorge A. Saraiva, Pavel Hradil, Tibor Liptaj, Lubomir Kobida, Miroslav Haban, Maria Holovicova and Dominika Zvercova
Sarcopoterium spinosum (L.) is a medicinal plant traditionally used for the treatment of various diseases including cancer in the Near- and Middle East. The fractions and constituents of the ethanol extract of S. spinosum were screened for in vitro cytot...
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Cecilia Di Ruberto, Andrea Loddo and Giovanni Puglisi
In microscopy, laboratory tests make use of cell counters or flow cytometers to perform tests on blood cells, like the complete blood count, rapidly. However, a manual blood smear examination is still needed to verify the counter results and to monitor p...
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