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Sufyan Danish, Asfandyar Khan, L. Minh Dang, Mohammed Alonazi, Sultan Alanazi, Hyoung-Kyu Song and Hyeonjoon Moon
Bioinformatics and genomics are driving a healthcare revolution, particularly in the domain of drug discovery for anticancer peptides (ACPs). The integration of artificial intelligence (AI) has transformed healthcare, enabling personalized and immersive ...
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Kristina Vukovic Ðerfi, Tea Vasiljevic and Tanja Matijevic Glavan
Head and neck squamous cell carcinoma (HNSCC) is a very heterogeneous cancer with a poor overall response to therapy. One of the reasons for this therapy resistance could be cancer stem cells (CSCs), a small population of cancer cells with self-renewal a...
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Gloria Perazzoli, Carolina de los Reyes, Cristina Pinedo-Rivilla, Rosa Durán-Patrón, Josefina Aleu, Laura Cabeza, Consolación Melguizo and Jose Prados
The marine environment is a promising source of natural products with possible pharmacological applications. In this sense, marine microorganisms, especially marine fungi, can produce bioactive compounds with various therapeutic properties. Colorectal ca...
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Bárbara Costa, Rita Matos, Irina Amorim, Fátima Gärtner and Nuno Vale
The breast cancer therapies available are insufficient, especially since first-line treatments, such as paclitaxel, result in drug resistance and their toxicity often limits their concentration. Strategies like drug repurposing are beneficial, and novel ...
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David Gomez Jimenez, Sofia Carreira Santos, Lennart Greiff, Kersti Alm and Malin Lindstedt
Cancer stem cells from oropharyngeal squamous cell carcinoma (OPSCC) have the ability to self-renew and differentiate into heterogeneous three-dimensional structures carrying features of tumor cells. Here, we describe a simple and label-free method for g...
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Paulina Natalia Osuchowska, Przemyslaw Wachulak, Agata Nowak-Stepniowska, Andrzej Bartnik, Kajangi Gnanachandran, Malgorzata Lekka, Joanna Czwartos, Henryk Fiedorowicz and Elzbieta Anna Trafny
This work is to study the relationship between the exposure conditions and the quality of cell imaging with soft X-ray contact microscopy (SXCM). It is a crucial step in the efficient visualization of cell structures. Three different human cell lines: DU...
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Ernesto Burgio, Prisco Piscitelli and Annamaria Colao
The dominant pathogenic model, somatic mutation theory (SMT), considers carcinogenesis as a ?genetic accident? due to the accumulation of ?stochastic? DNA mutations. This model was proposed and accepted by the scientific community when cancer mainly affe...
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Robert Snyder
Excessive exposure to benzene has been known for more than a century to damage the bone marrow resulting in decreases in the numbers of circulating blood cells, and ultimately, aplastic anemia. Of more recent vintage has been the appreciation that an alt...
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