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Rejane Viana, Ana C. Rocha, André P. Sousa, Diogo Ferreira, Rúben Fernandes, Cátia Almeida, Patrick J. Pais, Pilar Baylina and Ana Cláudia Pereira
Colorectal cancer (CRC) is the third most common cancer diagnosed today and the third leading cause of death among cancer types. CRC is one of the gastrointestinal tumors with obesity as the main extrinsic risk factor, since, according to authors, the me...
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António Pedro Branco, Cátia Vaz and Alexandre P. Francisco
There are several tools available to infer phylogenetic trees, which depict the evolutionary relationships among biological entities such as viral and bacterial strains in infectious outbreaks or cancerous cells in tumor progression trees. These tools re...
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Julia Figueroa-Martínez, Dulcenombre M. Saz-Navarro, Aurelio López-Fernández, Domingo S. Rodríguez-Baena and Francisco A. Gómez-Vela
Gene networks have become a powerful tool for the comprehensive examination of gene expression patterns. Thanks to these networks generated by means of inference algorithms, it is possible to study different biological processes and even identify new bio...
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Kristina Vukovic Ðerfi, Tea Vasiljevic and Tanja Matijevic Glavan
Head and neck squamous cell carcinoma (HNSCC) is a very heterogeneous cancer with a poor overall response to therapy. One of the reasons for this therapy resistance could be cancer stem cells (CSCs), a small population of cancer cells with self-renewal a...
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Cristina Mesas, Beatriz Segura, Gloria Perazzoli, Maria Angeles Chico, Javier Moreno, Kevin Doello, Jose Prados and Consolación Melguizo
Rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children, constitutes approximately 40% of all recorded soft tissue tumors and is associated with a poor prognosis, with survival rates of less than 20% at 3 years. The development of resista...
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Gloria Perazzoli, Carolina de los Reyes, Cristina Pinedo-Rivilla, Rosa Durán-Patrón, Josefina Aleu, Laura Cabeza, Consolación Melguizo and Jose Prados
The marine environment is a promising source of natural products with possible pharmacological applications. In this sense, marine microorganisms, especially marine fungi, can produce bioactive compounds with various therapeutic properties. Colorectal ca...
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Nermin Abdelhakim Othman, Manal A. Abdel-Fattah and Ahlam Talaat Ali
Because of technological advancements and their use in the medical area, many new methods and strategies have been developed to address complex real-life challenges. Breast cancer, a particular kind of tumor that arises in breast cells, is one of the mos...
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Kalidoss Rajendran, Ponmurugan Karuppiah, Ponmurugan Ponnusamy, Mohammed Rafi Shaik, Mujeeb Khan, Tae Hwan Oh and Baji Shaik
Thousands of different kinds of lichen metabolites are being examined for their biological activities, including anticancer properties. In this context, the present study aims to assess the anti-inflammatory activity of the acetone extract of Parmotrema ...
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Tsvetelina Batsalova, Alexander Vasil?kov, Dzhemal Moten, Anastasiia Voronova, Ivanka Teneva, Alexander Naumkin and Balik Dzhambazov
Bimetallic nanoparticles (BMNPs) combine unique and synergistic properties of two metals, allowing new specific applications. In this study, bimetallic AuFe nanoparticles and their conjugates with methotrexate (MTX) were obtained with an environmentally ...
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Alexander Dierlamm, Matthias Balzer, Felix Ehrler, Ulrich Husemann, Roland Koppenhöfer, Ivan Peric, Martin Pittermann, Bogdan Topko, Alena Weber, Stephan Brons, Jürgen Debus, Nicole Grau, Thomas Hansmann, Oliver Jäkel, Sebastian Klüter and Jakob Naumann
Particle therapy is a well established clinical treatment of tumors. More than one hundred particle therapy centers are in operation world-wide. The advantage of using hadrons like protons or carbon ions as particles for tumor irradiation is the distinct...
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