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Andrew Carter, Seth Racey and Stephany Veuger
Iron is a key metal involved in several biological processes such as DNA replication and repair, cellular proliferation and cell cycle regulation. Excess volumes of labile iron are toxic and can lead to the production of ROS (reactive oxygen species) via...
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Min Jeong Hong, Dae Yeon Kim, Yeong Deuk Jo, Hong-Il Choi, Joon-Woo Ahn, Soon-Jae Kwon, Sang Hoon Kim, Yong Weon Seo and Jin-Baek Kim
Gamma rays as a type of ionizing radiation constitute a physical mutagen that induces mutations and could be effectively used in plant breeding. To compare the effects of gamma and ionizing irradiation according to exposure time in common wheat (Keumgang...
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Ayan Barbora, Shailendra Rajput, Konstantin Komoshvili, Jacob Levitan, Asher Yahalom and Stella Liberman-Aronov
Non-ionizing millimeter-waves (MMW) interact with cells in a variety of ways. Here the inhibited cell division effect was investigated using 85?105 GHz MMW irradiation within the International Commission on Non-Ionizing Radiation Protection (ICNIRP) non-...
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Valerio Ricciardi, Marianna Portaccio, Lorenzo Manti and Maria Lepore
The ability of Fourier transform infrared (FTIR) spectroscopy in analyzing cells at a molecular level was exploited for investigating the biochemical changes induced in protein, nucleic acid, lipid, and carbohydrate content of cells after irradiation by ...
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Veronika Papp-Kádár; Zoltán Balázs, Gergely N. Nagy, Tünde Juhász, Károly Liliom, Beáta G. Vértessy
Pág. 51 - 56
Repair of DNA damage relies on various pathways including the base excision repair (BER) which targets erroneous bases in the DNA. Here, Uracil-DNA glycosylases (UDGs) are responsible for recognition and removal of uracil base from the DNA. Here, we char...
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Yuri A. Eidelman,Svetlana V. Slanina,Valentina S. Pyatenko,Sergey G. Andreev
Pág. 42 - 45
The origin of dose-response curves for radiation-induced chromosomal instability (CI) is studied using the mechanistic CI model. The model takes into account DNA damage generation and repair in the progeny of irradiated cells and cell passage through mit...
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K.R. Hartop, M.J. Sullivan, G. Giannopoulos, A.J. Gates, ... D.J. Richardson
Pág. 207 - 214
Nitrite, in equilibrium with free nitrous acid (FNA), can inhibit both aerobic and anaerobic growth of microbial communities through bactericidal activities that have considerable potential for control of microbial growth in a range of water systems. The...
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Ida Casorelli, Cecilia Bossa and Margherita Bignami
Most antitumour therapies damage tumour cell DNA either directly or indirectly. Without repair, damage can result in genetic instability and eventually cancer. The strong association between the lack of DNA damage repair, mutations and cancer is dramatic...
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